MSV3d provides full annotation of missense variants of all human proteins with multi-level characterization including details of the physico-chemical changes induced by the amino acid modification, information related to the conservation of the mutated residue and its position relative to functional features in available or calculated 3D model. The major release of the MSV3d database is automatically generated and updated regularly according to the dbSNP 135 (database of Single Nucleotide Polymorphism) and SwissVar releases.

Search by gene, Chr position
(e.g MTM1, HOXA2, BBS1, chr12:104187732, chr12:104187732-104187792)
Search by protein or PDB
(e.g Q13496, MTM1_HUMAN, O43364, 2i13, PF00001)
Search by identifiers in dbSNP
(e.g rs119489104)
Search by phenotype
(e.g myopathy, MIM:612290, HP:0000393)

Please cite: Luu, T.D., Rusu, A.M., Walter, V., Ripp, R., Moulinier, L., Muller, J., Toursel, T., Thompson, J.D., Poch, O., and Nguyen, H. (2012). MSV3d: database of human MisSense variants mapped to 3D protein structure. Database (Oxford) 2012, bas018.
doi: 10.1093/database/bas018

Contact: Hoan Nguyen(PhD,bmhoan@gmail.com)